Dr. Ertan Beyatlı

Remedy for Genital Wart (CONDILOMA)

(Update: ) - Skin and soft tissue diseases

Genital warts are one of the most common types of sexually transmitted infections. All sexually active people are infected with the virus (Human papilloma virus HPV) that causes genital warts at some point in their lifetime. The infection rate is higher in women.

As the name suggests, genital wart affects the moist tissue of the genital area. Genital warts can look like small, flesh-colored bumps or have a cauliflower-like appearance. In most cases, the warts are too small to be seen.

genital warts

Like warts seen elsewhere in your body, genital warts are caused by the human papilloma virus (HPV). Some strains of genital HPV can cause cancer. Vaccines can help protect against some genital HPV strains.


WomenGenital warts may grow on the vulva, the walls of the vagina, the area between the external genital organs and the anus (colloquially between the crotch), the anal canal and the cervix.

males may occur in the penis, bags (scrotum), or the tip or shaft of the anus. Genital warts can also develop in the mouth or throat of a person who has oral sexual contact with an infected person.

Genital warts signs and symptoms include:

  • Small, tan or gray-colored swelling in the genital area
  • Several closely spaced warts that take a cauliflower-like shape
  • Itching or discomfort in the genital area
  • Bleeding during intercourse

Genital warts can be so small and flat that they cannot be seen with the naked eye. However, sometimes, genital warts can multiply in large clusters.

When to see a doctor

If you or your partner or partner develops genital swelling or warts, see a doctor.



Human papilloma virus (HPV) causes warts. There are more than 40 different HPV strains that specifically affect the genital area. Genital HPV is spread through sexual intercourse. In fact, in most cases, the immune system kills this virus and the signs or symptoms of the infection never develop.

Risk factors

It is possible to predict that almost all people who work in the Centers for Disease Control and Prevention and who are sexually active will be infected with at least one type of HPV at some point in their lifetime. Factors that can increase the risk of infection include:

  • Having unprotected sex with multiple partners
  • Having had another sexually transmitted infection
  • Having sex with a partner whose sexual history you don't know
  • Being sexually active at a young age


Genital wart complications can include:

Cancer. Cervical cancer has been closely linked to genital HPV infection. Some HPV types are also associated with vulvar cancer, anal cancer, penile cancer, and mouth and throat cancer. Human papillomavirus infection does not always lead to cancer, but it is still important for women to have regular Pap tests, especially if you have higher-risk forms of HPV.

Problems in pregnancy. Genital warts can cause problems during pregnancy. Warts can enlarge and make it difficult to urinate. Warts on the vaginal wall can reduce the ability of the vaginal tissues to stretch during childbirth. Large warts on the vulva or vagina may bleed when they are stretched during childbirth. Rarely, a baby born to a mother with genital warts may develop warts in the throat.


Using condoms every time you have sex can significantly reduce your risk of getting genital warts. Although condom use does reduce your risk, it is not 100 percent effective. There is still a possibility of getting genital warts.


A vaccine known as Gardasil protects against four cancer-causing HPV strains and is used to prevent genital warts. In 2014, the U.S. Food and Drug Administration approved a vaccine called Gardasil 9 that protects against nine HPV strains.


Since genital warts are often difficult to detect, your doctor may apply a mild acetic acid solution to your genitals to whiten the warts. Later, he can see them with a special magnifying tool, a colposcope.

Pap tests

How is the Pap test done?

For women, it's important to have regular pelvic exams and Pap tests that can help detect vaginal and cervical changes of genital warts or early signs of vaginal cancer - this is a possible complication of genital HPV infection.

During the Pap test, your doctor will use a device called a speculum to hold your vagina open. He will then use a long-handled instrument to collect a small sample of cells from your cervix - the transition between your vagina and your uterus. Cells are examined under a microscope for abnormalities.

HPV test
Only a few types of genital HPV have been linked to cervical cancer. A sample of cervical cells taken during the Pap test can be tested for these cancer-causing HPV strains.

This test is generally reserved for women aged 30 and over. It is not beneficial for young women because their immune systems can kill the often noncancerous types of genital HPV without treatment.


If the warts do not bother you, you may not need treatment. But if your symptoms include itching, burning, and pain, or if visible warts are causing emotional and social distress, your doctor can help you clear an outbreak with medication or surgery. However, the lesions are likely to come back after treatment. There is no cure for the virus itself.


Genital wart treatments that can be applied directly to your skin include:

Imiquimod (Aldara, Zyclara). This cream works to increase your immune system's ability to fight genital warts. Avoid sexual contact while the cream is on your skin. This cream can thin condoms and irritate your partner's skin.

A possible side effect is redness of the skin. Other side effects may include blisters, body aches, cough, rashes, and tiredness.

Podophyllin and podofilox (Condylox). Podophyllin is a plant-based resin that destroys genital wart tissue. Your doctor should apply this solution. Podofilox contains the same active ingredient and can be safely administered by you at home.

Your doctor may want to apply the first application of podofilox and will recommend precautionary measures to prevent the medication from irritating the surrounding skin. Never apply podofilox internally. In addition, this drug is not recommended for use during pregnancy. Side effects can include mild skin irritation, sores, or pain.

Trichloroacetic acid (TCA). This chemical process burns genital warts and can be used for internal warts. Side effects can include mild skin irritation, sores, or pain.

Cinecatechins (Veregen). This cream is used to treat external genital warts and warts in or around the anal canal. Side effects are usually mild and may include skin rash, itching or burning and pain.

Note: Genital wart is a viral infection. So the cause is the virus (HPV). Therefore, anti-bacterial creams, which are widely known in the society (Fucidin, Bactroban, Teramycin, etc.) has no effect on genital warts.

Surgical Treatment Option

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Surgery may be needed to remove large warts, warts that do not respond to medications, or - if you are pregnant - warts your baby may have been exposed to during labor. Surgical options include:

  • Freezing with liquid nitrogen (cryotherapy). Freezing works by causing a bubble to form around your wart. As your skin heals, the lesions swell and allow new skin to appear. You may need repeated cryotherapy treatments. Its main side effects include pain and swelling.
  • Electrocautery. This procedure uses electric current to burn the warts. There may be some pain and swelling after the procedure.
  • Surgical excision. Radical solution. Your doctor can use special tools to cut the warts. You will need local or general anesthesia for this treatment and there may be some pain afterwards.
  • Laser therapy. Using an intense beam of light, this approach can be expensive and is often reserved for very extensive and difficult to treat warts. Side effects can include scarring and pain.

What not to do

  • Do not use imiquimod, podofilox or podophyllin during pregnancy. These agents are not safeguarded during pregnancy, and there have been several reported cases of toxicity when using large amounts of podophilin.
  • Do not confuse the penile wart (Figure-1) with the "pearl penile papules" on the penis (Figure-2). Dome-shaped or hair-shaped protrusions around the corona of the glans penis are normal variants in 10% of men.
  • Do not confuse condyloma acuminatum disease with other lesions. For example: Condylotata lata, Vulva micropapilluma powder, Molluscum contagiosum and Squamous cell carcinoma. If the lesions do not respond to treatment, consider a biopsy.
  • Recurrence is inherent in the normal nature of this disease. Share this information with patients.
Figure-1: Genital Warts with Penis Warts
Figure-1: Penis Warts
Figure-2: Pearl penile papules
Figure-2: Pearl penile papules
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